Due to COVID-19 and for the safety of our facility and patients, we ask that you come into the office with a face mask on and to make sure you do not have a temperature above 100 degrees.

Understanding Nephrotic Syndrome and Recognizing Its Symptoms

Understanding Nephrotic Syndrome and Recognizing Its Symptoms

Nephrotic syndrome is a rare but serious kidney condition that causes a spillage of protein into the urine. The result is various symptoms that signal a problem within the kidneys that a specialist needs to address.

If you're living with chronic kidney disease or other kidney disorders, the specialists at Metro Renal Associates offer a range of diagnostic tools and treatments to help maintain the health of your urinary system.

Our team of three experienced nephrologists offers urine testing for blood in the urine and proteinuria, which can signal nephrotic syndrome or other severe kidney diseases.

What is nephrotic syndrome?

Nephrotic syndrome is a problem where the filters (glomeruli) within the kidney are damaged, allowing protein to leak out into the urine. The glomeruli are small vessels that are responsible for filtering out excess fluids and wastes from urine.

People with nephrotic syndrome have damaged glomeruli that allow more than three grams of protein to seep into the urine over 24 hours. It's about 20 times more protein than healthy glomeruli allow to pass in a healthy person.

Causes of nephrotic syndrome

Nephrotic syndrome is a rare condition, but it does happen. Both children and adults are at risk if they have certain conditions that include:

  • Minimal change disease
  • Lupus
  • Membranous glomerulonephritis
  • Diabetes-related nephropathy
  • Certain infections
  • Amyloidosis

Just because you have one of the above conditions doesn't automatically mean you'll develop nephrotic syndrome. However, the risk increases for the condition without proper kidney care and a focus on your health.

Signs and symptoms to know

Knowing the signs and symptoms of nephrotic syndrome could save your life. The symptoms directly correlate with damaged glomeruli, which allows the protein to leak into the urine.

Excess protein in the urine leads to various signs and symptoms of nephrotic syndrome, which include the following:

  • Proteinuria in a urine test
  • Foamy urine
  • Weight gain from fluid retention
  • Swelling in the legs and ankles
  • Loss of appetite
  • Feeling unwell
  • Abdominal or flank pain
  • Higher than usual cholesterol levels

The symptoms may develop suddenly or over time. You need to seek treatment as soon as possible to avoid complications from nephrotic syndrome. The longer the symptoms persist, the more likely you are to have hypertension and acute kidney injury.

Diagnosing the problem

If we suspect nephrotic syndrome, the first step is a urinalysis. We provide you with a cup to collect a urine sample, which we will test for excess protein. Proteinuria is one of the key signs of nephrotic syndrome.

We also test for other substances in the urine, such as albumin levels and creatinine. You may need to provide several urine samples at different times throughout the day to obtain an accurate reading.

Blood tests are also crucial in diagnosing nephrotic syndrome. We test for albumin levels and triglyceride levels to diagnose nephrotic syndrome.

The goal of treatment is to address the underlying condition causing damage to the glomeruli. With treatment, most people go into remission from nephrotic syndrome.

To learn more about nephrotic syndrome and our treatments, call one of our conveniently located offices in Washington, D.C., and Capitol Heights, Maryland. You can also request a consultation on the website.

You Might Also Enjoy...

Life After Your Kidney Transplant: What to Expect

After a kidney transplant, life changes slightly, but you may not know what to expect. Read on to learn how life changes after a kidney transplant and tips to stay healthy while your body adjusts to the new organ.
Is Bloody Urine a Medical Emergency?

Is Bloody Urine a Medical Emergency?

Seeing blood in the toilet is terrifying, especially if you don't know where it originated. Read on to learn when bloody urine is an emergency and the next steps in treatment for peace of mind.
5 Encouraging Facts About Polycystic Kidney Disease

5 Encouraging Facts About Polycystic Kidney Disease

A PKD diagnosis is scary, especially when all you read about is the negatives – but there are some encouraging facts about PKD. Learn more about living with PKD and the positives that you can expect from treatment.
 What is Edema and How is it Treated?

What is Edema and How is it Treated?

Edema is a problem resulting from fluid build-up in the tissues – but can you eliminate it? Find out more about edema, the symptoms to watch for, and successful treatments that offer long-term relief.